0000297011 00000 n For multiple injections, injection sites should be alternated. See Safety info. Do not warm up using a heat source such as hot water or a microwave. fremanezumab 225mg solution for injection in pre-filled syringe (Ajovy®) Teva UK Limited 6 December 2019 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHSScotland. 1. For more information click here or call us on 020 7251 3322. 0000008774 00000 n 0000022286 00000 n 0000116590 00000 n The new Ajovy pre-filled pen, developed in the UK at Teva’s research and development site in Abbots Park, Cheshire, includes a button-free, push-down mechanism, audible cues that signal progress of administration, and a window that displays when the dose has been delivered. AJOVY (fremanezumab-vfrm) injection is a sterile, preservative-free, clear to opalescent, colorless to slightly yellow solution for subcutaneous injection, supplied in a single-dose 225 mg/1.5 mL prefilled autoinjector and a single-dose 225 mg/1.5 mL prefilled syringe. 0000300290 00000 n Tools & Resources For Patients | AJOVY® (fremanezumab-vfrm) injection. trailer <<8AE087A73DF44EEA8C5B746CB2C90974>]/Prev 920701/XRefStm 3274>> startxref 0 %%EOF 520 0 obj <>stream 0000017452 00000 n 0000020835 00000 n 0000014316 00000 n *��?�y�����),c"ܷ���J�a�{��c��/���ڜ�b����M���g�]ۺ{v�����ao�L���^���y�tq�xkt��ջw����������'J���s2ٙ9�/� �O��`��QU��VZX�G�)���8-�uv�^���O��?�9C��9|� [}"�fq�\T�#G��9b��b�,4�DT��'̞�e".+8Rw�YB��1���sZ�g�0֋��Hc�ENy�;ç������ 0000294224 00000 n 0000304112 00000 n Keep AJOVY Autoinjector out of the reach of small children. “A pen device which patients can easily self-administer will reduce appointments and waiting times. 0000291861 00000 n Teva UK has launched a pre-filled pen for Ajovy (fremanezumab) injection, offering patients with migraine a more convenient and flexible dosing option than with a syringe, which can be self-administered in the home. Ajovy is indicated for the prevention of migraine in adults who have at least four migraine days per month, with quarterly and monthly dosing options. EFFICACY OF AJOVY®. Several months after turning down NHS funding for Novartis’ CGRP inhibitor Aimovig for migraine prevention, NICE has backed another drug in the class – Teva’s Ajovy – in draft guidance. This option will also be welcomed by my patients, who can travel 2-3 hours to the clinic for appointments.”. AJOVY® can be injected into areas of the abdomen, thigh, or upper arm that are not tender, bruised, red or indurated. 0000149387 00000 n AJOVY is the long acting anti-CGRP injection with the option of dosing just 4 times a year. Keep AJOVY prefilled syringe out of the reach of small children. 0000087073 00000 n If their healthcare professional thinks that Ajovy is the right medicine for you, then you should be able to have that treatment on the NHS. 0000116404 00000 n Adverse Reactions: The most common adverse reactions (≥5% and greater than placebo) were injection site reactions. 0000003458 00000 n Indication. 0000070289 00000 n Manufacturer advises injection into the abdomen, thigh or upper arm. 0000105197 00000 n H���=h�U��0�}ɋy�E��8p1���dp)n1� 5�C���E�i�`����E�^i�.��`=��. It can be injected into areas of the abdomen, thigh, or upper arm that are not tender, bruised, red or indurated. At NMC our headache specialists can prescribe Ajovy privately until it is available on the NHS across the UK. 0000005027 00000 n 0000116338 00000 n 0000048107 00000 n Ajovy is usually given as 1 injection once a month, or as 3 injections (in separate syringes) once every 3 months. When Ajovy first came on the market, it came in a pre-filled syringe, like you would see in a doctor’s office. It should not be administered by the intravenous or intramuscular route. See safety info. 0000009924 00000 n 0000010595 00000 n 0000300444 00000 n 0000027270 00000 n 0000308307 00000 n Please see the Full Prescribing Information for AJOVY® Adverse events should be reported. 0000020539 00000 n Ajovy (fremanezumab) 225 mg Pre-filled Syringe for Injection - Patient Information Leaflet (PIL) by Teva UK Limited Each pre-filled syringe contains 1.5 mL solution. Adverse Events: The most common adverse reactions were injection site reactions 1. For multiple injections, injection sites should be alternated. It is the first and only anti-CGRP drug recommended for use on the NHS in England and Wales for chronic migraine patients, and within Scotland for chronic and episodic migraine, after other therapies have failed. 0000039799 00000 n 0000087224 00000 n 0000162249 00000 n 0000105310 00000 n 0000008851 00000 n 402 0 obj <> endobj xref It should not be administered by the intravenous or intramuscular route. For multiple injections, injection sites should be alternated. 0000122201 00000 n Do not warm up using a heat source such as hot water or a microwave. 0000291822 00000 n 0000296548 00000 n 0000105081 00000 n 0000020231 00000 n ! Please see the Full Prescribing Information for AJOVY® Adverse events should be reported. 0000070093 00000 n For further instructions on administration, see section 6.6. AJOVY 225 mg solution for injection in pre-filled pen fremanezumab Before you use the AJOVY pre-filled pen, read and carefully follow the step-by-step instructions. 0000029797 00000 n 0000006264 00000 n Find out if AJOVY is right for you and sign up for updates. 0000122715 00000 n Before injecting, let AJOVY sit at room temperature for 30 minutes. 0000013505 00000 n After you remove the needle cap, to prevent infection, do not touch the needle. The AJOVY pre-filled pen is for single use only. 0000122471 00000 n AJOVY can be injected into areas of the abdomen, thigh, or upper arm that are not tender, bruised, red, or indurated. Significantly more migraine-free days vs placebo 1-5. 0000105232 00000 n 0000116681 00000 n Ajovy is a calcitonin gene-related peptide antagonist indicated for the preventive treatment of migraine in adults. 0000104687 00000 n 0000149426 00000 n Adverse Events: The most common adverse reactions were injection site reactions 1. However, headache/migraine specialist clinics are often challenged by high caseloads,” added Neurology Nurse Prescriber Rebecca Stuckey, University Hospitals Plymouth NHS Trust. “Fremanezumab is well tolerated, effective and particularly useful for complex migraine patients, where other treatments have failed. %PDF-1.4 %���� 0000087007 00000 n 0000312298 00000 n 0000007722 00000 n 0000304655 00000 n AJOVY is for subcutaneous injection only. 0000296470 00000 n 0000020701 00000 n 0000009810 00000 n 0000006525 00000 n 0000069663 00000 n Patients may self-inject if instructed in subcutaneous self-injection technique by a healthcare professional. 0000308229 00000 n 0000136204 00000 n Book Now! The new Teva autoinjector also has several features that make it easy-to-use 1 including a button-free, push-down mechanism; audible cues that signal progress of administration; and, a window that displays when the dose has been delivered. T: +44 (0)20 7240 6999 0000014815 00000 n Read and carefully follow any Instructions for Use provided with your medicine. If a hypersensitivity reaction occurs, consider discontinuing AJOVY and institute appropriate therapy. Patients are often worried about using traditional syringes to inject themselves. AJOVY is available as a 225 mg/1.5mL single dose injection in a prefilled syringe with two dosing options – 225 mg monthly administered as one subcutaneous injection, or 675 mg every three months (quarterly), administered as three subcutaneous injections. Indication. 0000003274 00000 n 0000239787 00000 n 0000007147 00000 n 0000048379 00000 n Little Bookham 0000039953 00000 n hތ�AhA����d�f�&i� 6uMmZkS���ŠkA��X ��HM[��h[��j�$�r�����ăЂ�Xr���B���c Felxibility of ajovy®. 0000018572 00000 n Flexibility to help you meet your patients’ needs 1,5. 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